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健康志愿者的尿直肠动力学评估。

Urorectodynamic evaluation of healthy volunteers.

作者信息

Abdel-Rahman M, Coulombe A, Devroede G, Toppercer A, Duguay C, Lapointe L, Elhilali M

出版信息

Urology. 1982 May;19(5):559-64. doi: 10.1016/0090-4295(82)90621-5.

DOI:10.1016/0090-4295(82)90621-5
PMID:6123175
Abstract

Twelve female and 8 male healthy volunteers underwent urorectodynamic evaluation. Mean bladder capacity was 594 ml. and mean maximal vesical pressure 12.5 cm. water (H2O). Maximal bladder pressure correlated significantly with maximal mural tension (r = 0.96) but did not correlate well with bladder capacity (r = 0.20). Mean bladder volume at first desire to void was 32 per cent of mean bladder capacity. The bladder volume at the first desire did not correlate significantly with the capacity. Mean bladder pressure at 100 ml. volume was 2.9 +/- 0.4 cm. H2O (X +/- SEM). After bethanechol injection, the bladder pressure at 100 ml. volume increased by 8.8 +/- 1.2 cm. H2O (X +/- SEM) at twenty minutes. In only 1 subject did bladder pressure rise higher than 15 cm. H2O (5 per cent). Rectal pressure increased from 1.4 +/- 0.3 to 14.1 +/- 2 cm. H2O (X +/- SEM) at sixteen minutes. Electromyogram (EMG) of the external and sphincter did not follow regular pattern with vesical filling or attempt of voiding. The data obtained in these normal subjects may serve as a basis for comparison in the interpretation of data obtained in patients.

摘要

12名女性和8名男性健康志愿者接受了尿直肠动力学评估。平均膀胱容量为594毫升,平均最大膀胱压力为12.5厘米水柱(H2O)。最大膀胱压力与最大壁张力显著相关(r = 0.96),但与膀胱容量相关性不佳(r = 0.20)。首次有排尿欲望时的平均膀胱容量为平均膀胱容量的32%。首次有排尿欲望时的膀胱容量与膀胱总容量无显著相关性。100毫升容量时的平均膀胱压力为2.9±0.4厘米水柱(X±SEM)。注射氨甲酰甲胆碱后,20分钟时100毫升容量的膀胱压力升高了8.8±1.2厘米水柱(X±SEM)。只有1名受试者的膀胱压力升高超过15厘米水柱(5%)。16分钟时直肠压力从1.4±0.3厘米水柱升高至14.1±2厘米水柱(X±SEM)。外括约肌的肌电图(EMG)在膀胱充盈或排尿尝试时未呈现规律模式。在这些正常受试者中获得的数据可作为解释患者数据时进行比较的基础。

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