Burri C, Lob G
Aktuelle Traumatol. 1982 Jun;12(3):159-65.
Removal of septic foci in putrid infection of the bone is an important step in the treatment of post-traumatic osteitis. The methods employed so far, such as through-drainage and siphonage, as well as gentamycin-PMMA chains, have very obvious drawbacks although they have definitely achieved favourable results. Taurolin Gel , a preparation consisting of denatured collagen in combination with the chemotherapeutic Taurolin 4%, is theoretically capable of eliminating these drawbacks. Clinical application appeared justified on the basis of good results obtained with the drainage solution of Taurolin, as well as in the course of experiments. Results have been obtained mostly in a single application in 50 cases documented and followed up; these results were equivalent to those obtained by means of the other methods. In consideration of the advantages with regard to application and effect, the authors believe that testing of this substance on a larger scale should be recommended.
去除骨的腐败性感染中的脓灶是创伤后骨髓炎治疗中的重要步骤。迄今为止所采用的方法，如贯穿引流和虹吸引流，以及庆大霉素 - 聚甲基丙烯酸甲酯链，尽管肯定取得了良好效果，但都有非常明显的缺点。托罗林凝胶是一种由变性胶原蛋白与4%化疗药物托罗林组合而成的制剂，理论上能够消除这些缺点。基于托罗林引流液取得的良好效果以及实验过程中的情况，临床应用似乎是合理的。在50例有记录和随访的病例中大多单次应用就取得了结果；这些结果与通过其他方法获得的结果相当。考虑到在应用和效果方面的优势，作者认为应该推荐对该物质进行更大规模的试验。
