Zawadziński S, Benke G, Eluszkiewicz S, Wasikowski A, Zarek S
Kliniki Ortopedycznej AM w Warszawie.
Chir Narzadow Ruchu Ortop Pol. 1990;55(2):145-8.
The activity and principles of administration of Taurolin have been presented. That drug was used in 15 patients with chronic osteitis. Healing by first intention was obtained in 10 patients, necrosis of the skin occurred in 3 patients, recurrence of inflammation was found in one patient in whom accessory sequestroctomy was performed in the last case of osteitis and arteriosclerosis healing was obtained by second intention. The clinical observation of 15 patients has revealed: a) irritating influence of Taurolin on the soft tissue, b) increased phase of secretion of exudate since the 5 day after surgery, c) bactericidal influence of the drug. Sterilization of the focus occurred at 2 to 3 weeks after surgery. The use of Taurolin requires experience, complete abiding by the principles of use of this drug and equipment with a set of Charrier's drains. The authors are carrying on further observation of the use of Taurolin in the treatment of osteitis.
已介绍了牛磺罗宁的活性及给药原则。该药物用于15例慢性骨炎患者。10例患者实现一期愈合，3例患者出现皮肤坏死，1例患者炎症复发，该例为骨炎最后1例且进行了附属死骨切除术，通过二期愈合实现动脉硬化愈合。对15例患者的临床观察显示：a）牛磺罗宁对软组织有刺激作用，b）术后第5天起渗出物分泌增加阶段，c）该药物的杀菌作用。术后2至3周病灶实现杀菌。使用牛磺罗宁需要经验，完全遵守该药物的使用原则以及配备一套夏里埃引流管。作者正在对牛磺罗宁在骨炎治疗中的应用进行进一步观察。
