Varma T R, Morsman J
Int J Gynaecol Obstet. 1982 Feb;20(1):13-7. doi: 10.1016/0020-7292(82)90039-x.
This study evaluates the effect of treatment with Proluton-Depot (hydroxyprogesterone hexanoate) in early pregnancy, and the final outcome of pregnancy and fetal status. One hundred and fifty patients received intramuscular injection of Proluton-Depot from 6 weeks to 8 weeks to 16 weeks to 18 weeks gestation. The outcome of this treated group was compared with a similar number of 150 patients with similar problems, but the second group received no hormonal treatment. There was no evidence to suggest that Proluton-Depot had any adverse effect on the infant or the final outcome of pregnancy.
本研究评估了孕早期使用普洛卢通长效注射剂（己酸羟孕酮）治疗的效果以及妊娠的最终结局和胎儿状况。150例患者在妊娠6周-8周、16周-18周时接受了普洛卢通长效注射剂的肌肉注射。将该治疗组的结局与150例有类似问题但未接受激素治疗的患者进行了比较。没有证据表明普洛卢通长效注射剂对婴儿或妊娠的最终结局有任何不良影响。
