Yang H
Xin Qiao Hospital, Chongqing.
Zhonghua Wai Ke Za Zhi. 1992 Oct;30(10):616-8, 636.
Plasma vasoactive intestinal peptide (VIP), blood glucose concentration and hematocrit (HCT) were measured in 15 patients after Billroth-II subtotal gastrectomy (B-II SG) and 8 healthy controls before and after oral glucose ingestion. In B-II SG group the rate of rise of VIP concentration was in positive correlation to the rate of rise of HCT (r = 0.501 P < 0.05) and to that of blood glucose (r = 0.715 P < 0.01). Also, the elevation rate of HCT blood glucose and VIP concentration was significant higher in B-II SG group than in controls (P < 0.05). It was found that the elevation rate of VIP concentration was much higher in patients with dumping syndrome after B-II SG than those without (P < 0.05). The results suggest that VIP may play a role in the pathogenesis of dumping syndrome.
在15例毕Ⅱ式胃大部切除术（B-II SG）患者和8名健康对照者口服葡萄糖前后，测定了血浆血管活性肠肽（VIP）、血糖浓度和血细胞比容（HCT）。在B-II SG组中，VIP浓度的上升速率与HCT的上升速率呈正相关（r = 0.501，P < 0.05），与血糖的上升速率也呈正相关（r = 0.715，P < 0.01）。此外，B-II SG组中HCT、血糖和VIP浓度的升高速率显著高于对照组（P < 0.05）。研究发现，B-II SG术后发生倾倒综合征的患者VIP浓度升高速率比未发生者高得多（P < 0.05）。结果表明，VIP可能在倾倒综合征的发病机制中起作用。
