Sheikhzadeh A, Ghabussi P, Razi M
Herz. 1982 Oct;7(5):325-30.
We report the findings in 26 cases of occlusive aortopathy (Takayasu's disease) encountered during eight years. The mean age was 25.3 years and female to male ratio was 2.7:1. Chest and local pain, fever, hypertension (70%) and absent pulses were accompanied by high erythrocyte sedimentation rate (ESR) 38 to 126 mm, eosinophilia 4 to 26%. All immunological tests were negative except tuberculin-test (PPD) with 65% positive. EKG was normal in three cases, 23 showed left ventricular hypertrophy, ST-T changes in two and acute myocardial infarction in two cases. The classification: Type I cervico-brachial or arch type with five cases, type II thoraco-abdominal type with six cases, type III peripheral type with four cases and generalized types combination of two or more of three types and/or pulmonary artery involvement, showed good correlation with clinical findings and prognosis. The occlusive aortopathy is an inflammatory disease of unknown origin, an auto-immune or genetic etiology may be involved.
我们报告了八年间遇到的26例闭塞性主动脉病（高安氏病）的研究结果。平均年龄为25.3岁，男女比例为2.7:1。胸部和局部疼痛、发热、高血压（70%）和脉搏消失伴有高红细胞沉降率（ESR）38至126mm，嗜酸性粒细胞增多4%至26%。除结核菌素试验（PPD）65%呈阳性外，所有免疫检查均为阴性。3例心电图正常，23例显示左心室肥厚，2例有ST-T改变，2例发生急性心肌梗死。分类：I型颈臂型或弓型5例，II型胸腹型6例，III型周围型4例，广义型为三种类型中的两种或更多种的组合和/或肺动脉受累，与临床表现和预后显示出良好的相关性。闭塞性主动脉病是一种病因不明的炎症性疾病，可能涉及自身免疫或遗传病因。
