Mukherjee D C, Agrawal A K, Manjunath R, Mukherjee A B
Science. 1983 Feb 25;219(4587):989-91. doi: 10.1126/science.6130601.
There is evidence that the mammalian female genital tract is capable of responding immunologically when challenged with alloantigens. The antigenic properties of male gametes have been well delineated. However, it is only rarely that a female mammal ever responds immunologically to the male gametic antigens as a result of coitus. When a proposed mechanism of suppression of antigenicity of epididymal spermatozoa was tested experimentally, the results indicated that two proteins (uteroglobin and transglutaminase) present in the prostate may be responsible for suppressing sperm antigenicity in the rabbit.
有证据表明，哺乳动物的雌性生殖道在受到同种异体抗原攻击时能够产生免疫反应。雄性配子的抗原特性已得到充分描述。然而，雌性哺乳动物很少会因性交而对雄性配子抗原产生免疫反应。当对一种提出的附睾精子抗原性抑制机制进行实验测试时，结果表明前列腺中存在的两种蛋白质（子宫珠蛋白和转谷氨酰胺酶）可能负责抑制兔子精子的抗原性。
