对兔附睾精子和精液精子自身免疫反应的检测。
Detection of autoimmune response to rabbit epididymal and seminal spermatozoa.
作者信息
Riera C M, Galmarini M, Faillaci M G, Yantorno C
出版信息
Int Arch Allergy Appl Immunol. 1980;62(2):231-4. doi: 10.1159/000232517.
Conventional and anaphylactic autoantibodies to rabbit epididymal and seminal spermatozoa were detected in sera of rabbits autoimmunized by several procedures. Antibodies against epididymal spermatozoa were found in 85% of rabbits showing lesions of varying degrees in testes. When the comparison was made with antibodies to antigens of spermatozoa from semen, the correlation was markedly lower. The data prove the importance of a proper selection of the antigenic material when looking for antibodies to spermatozoa in studies of autoimmunity and fertility.
通过多种程序对兔子进行自身免疫后，在其血清中检测到了针对兔附睾和精液精子的常规自身抗体及过敏反应性自身抗体。在85%睾丸出现不同程度病变的兔子中发现了抗附睾精子的抗体。当与针对精液中精子抗原的抗体进行比较时，相关性明显较低。这些数据证明了在自身免疫和生育力研究中寻找精子抗体时，正确选择抗原物质的重要性。
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