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兔和野兔垂体中间部的催产素免疫反应性神经纤维。

Oxytocin-immunoreactive nerve fibers in the pars intermedia of the pituitary in the rabbit and hare.

作者信息

Schimchowitsch S, Stoeckel M E, Klein M J, Garaud J C, Schmitt G, Porte A

出版信息

Cell Tissue Res. 1983;228(2):255-63. doi: 10.1007/BF00204877.

DOI:10.1007/BF00204877
PMID:6130846
Abstract

The pars intermedia of the pituitary in the rabbit and hare is abundantly innervated by axons reacting selectively with antibodies against oxytocin. These axons contain dense secretory vesicles about 140 nm in diameter, i.e., smaller than those in the neurosecretory axons of the neural lobe. No fiber elements staining for other peptides (vasopressin, somatostatin, substance P) were observed in the pars intermedia, except rare leu-enkephalin axons restricted to the rostral zone of the gland. Dopaminergic innervation appears to be completely absent from the intermediate lobe. This was shown by the lack of reaction with an antibody against tyrosine-hydroxylase, which did reveal a well-developed tubero-infundibular system of nerve fibers. Axons reacting with an antibody against serotonin were irregularly distributed in the pars intermedia. In the absence of dopaminergic axons, the extensive oxytocin-like innervation may play a major role in regulating the melanotrophic cell activity in the Leporidae.

摘要

兔和野兔垂体的中间部有丰富的轴突支配,这些轴突能与抗催产素抗体发生选择性反应。这些轴突含有直径约140纳米的致密分泌小泡,即比神经叶神经分泌轴突中的小泡小。在中间部未观察到其他肽(加压素、生长抑素、P物质)染色的纤维成分,仅在腺体头端区域有罕见的亮脑啡肽轴突。中间叶似乎完全没有多巴胺能神经支配。这通过与抗酪氨酸羟化酶抗体缺乏反应得以证明,而该抗体确实显示出发育良好的结节漏斗神经纤维系统。与抗血清素抗体反应的轴突不规则地分布在中间部。在没有多巴胺能轴突的情况下,广泛的催产素样神经支配可能在调节兔科动物黑素营养细胞活性中起主要作用。

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Systematic presence of GABA-immunoreactivity in the tubero-infundibular and tubero-hypophyseal dopaminergic axonal systems: an ultrastructural immunogold study on several mammals.γ-氨基丁酸免疫反应性在结节漏斗和结节垂体多巴胺能轴突系统中的系统性存在:对几种哺乳动物的超微结构免疫金研究
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