Millar R P, Sheward W J, Wegener I, Fink G
Brain Res. 1983 Feb 7;260(2):334-7. doi: 10.1016/0006-8993(83)90692-3.
Somatostatin 14 and 28 (SS-14 and SS-28) have been measured in hypophysial portal blood of male Wistar rats. The concentration and total amount of SS released into portal blood were increased 6- to 7-fold by electrical stimulation of the median eminence. On HPLC, only two peaks of immunoreactivity were detected in extracts of portal plasma and these peaks corresponded with SS-14 and SS-28, respectively. The amount of SS-28 in portal plasma was, on a molar basis, similar or greater than that of SS-14 and this together with other evidence suggests that SS-28 is an hormonally active peptide.
已对雄性Wistar大鼠垂体门脉血中的生长抑素14和28（SS - 14和SS - 28）进行了测定。通过电刺激正中隆起，释放到门脉血中的SS浓度和总量增加了6至7倍。在高效液相色谱法中，在门脉血浆提取物中仅检测到两个免疫反应峰，且这些峰分别与SS - 14和SS - 28相对应。以摩尔计，门脉血浆中SS - 28的量与SS - 14相似或更高，这与其他证据一起表明SS - 28是一种具有激素活性的肽。
