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生长抑素-28(1-12)样免疫反应性物质分泌到大鼠的垂体门脉血管血液中。

Somatostatin-28(1-12)-like immunoreactive substance is secreted into hypophysial portal vessel blood in the rat.

作者信息

Sheward W J, Benoit R, Fink G

出版信息

Neuroendocrinology. 1984 Jan;38(1):88-90. doi: 10.1159/000123871.

DOI:10.1159/000123871
PMID:6694786
Abstract

Somatostatin-28(1-12)-like immunoreactivity was measured in extracts of rat hypophysial portal blood and peripheral blood. The concentration of somatostatin-28(1-12) was higher in portal than in peripheral extracts, and its release into portal vessel blood was increased 4- to 5-fold by electrical stimulation of the median eminence. These results show that somatostatin-28(1-12) may be a physiological neurohormone and/or neurotransmitter.

摘要

在大鼠垂体门脉血和外周血的提取物中测量了生长抑素-28(1-12)样免疫反应性。垂体门脉血中生长抑素-28(1-12)的浓度高于外周提取物中的浓度,通过电刺激正中隆起,其向门脉血管血中的释放增加了4至5倍。这些结果表明,生长抑素-28(1-12)可能是一种生理性神经激素和/或神经递质。

相似文献

1
Somatostatin-28(1-12)-like immunoreactive substance is secreted into hypophysial portal vessel blood in the rat.生长抑素-28(1-12)样免疫反应性物质分泌到大鼠的垂体门脉血管血液中。
Neuroendocrinology. 1984 Jan;38(1):88-90. doi: 10.1159/000123871.
2
Dopamine in plasma of lateral and medial hypophysial portal vessels: evidence for regional variation in the release of hypothalamic dopamine into hypophysial portal blood.垂体外侧和内侧门脉血管血浆中的多巴胺:下丘脑多巴胺释放至垂体门脉血存在区域差异的证据。
Endocrinology. 1983 Jun;112(6):1958-63. doi: 10.1210/endo-112-6-1958.
3
Somatostatin-28 is an hormonally active peptide secreted into hypophysial portal vessel blood.生长抑素-28是一种分泌到垂体门脉血管血液中的具有激素活性的肽。
Brain Res. 1983 Feb 7;260(2):334-7. doi: 10.1016/0006-8993(83)90692-3.
4
Many peptides that are present in the external zone of the median eminence are not secreted into the hypophysial portal blood of sheep.
Neuroendocrinology. 1993 May;57(5):765-75. doi: 10.1159/000126435.
5
Hypothalamo-hypophysial blood flow: a novel control mechanism in pituitary function?下丘脑 - 垂体血流:垂体功能中的一种新型控制机制?
J Endocrinol. 1987 Apr;113(1):R1-2. doi: 10.1677/joe.0.113r001.
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Effect of intraventricular injection of neurotensin and other various bioactive peptides on plasma immunoreactive somatostatin levels in rat hypophysial portal blood.脑室内注射神经降压素及其他多种生物活性肽对大鼠垂体门脉血中血浆免疫反应性生长抑素水平的影响。
Endocrinology. 1981 May;108(5):1939-43. doi: 10.1210/endo-108-5-1939.
7
Enhancement of immunoreactive somatostatin release into hypophysial portal blood by electrical stimulation of the preoptic area in the rat.电刺激大鼠视前区增强免疫反应性生长抑素向垂体门脉血中的释放。
Endocrinology. 1979 Dec;105(6):1416-8. doi: 10.1210/endo-105-6-1416.
8
Stimulation by bombesin of immunoreactive somatostatin release into rat hypophysial portal blood.蛙皮素刺激免疫反应性生长抑素释放至大鼠垂体门脉血中。
Endocrinology. 1981 Jul;109(1):229-34. doi: 10.1210/endo-109-1-229.
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Immunoreactive somatostatin in rat hypophysial portal blood.大鼠垂体门脉血中的免疫反应性生长抑素。
Endocrinology. 1979 May;104(5):1407-10. doi: 10.1210/endo-104-5-1407.
10
beta-Endorphin is present in high concentration in the hypophysial portal vessels of rats.β-内啡肽在大鼠垂体门脉血管中含量很高。
Neurosci Lett. 1980 Sep;19(2):191-5. doi: 10.1016/0304-3940(80)90193-7.

引用本文的文献

1
Neuronostatin is co-expressed with somatostatin and mobilizes calcium in cultured rat hypothalamic neurons.神经元抑制素与生长抑素共表达,并在培养的大鼠下丘脑神经元中动员钙。
Neuroscience. 2010 Mar 17;166(2):455-63. doi: 10.1016/j.neuroscience.2009.12.059. Epub 2010 Jan 4.
2
Molecular biology of the regulation of hypothalamic hormones.下丘脑激素调节的分子生物学
J Endocrinol Invest. 1993 Mar;16(3):219-46. doi: 10.1007/BF03344952.