生长抑素-28(1-12)样免疫反应性物质分泌到大鼠的垂体门脉血管血液中。

Somatostatin-28(1-12)-like immunoreactive substance is secreted into hypophysial portal vessel blood in the rat.

作者信息

Sheward W J, Benoit R, Fink G

出版信息

Neuroendocrinology. 1984 Jan;38(1):88-90. doi: 10.1159/000123871.

Abstract

Somatostatin-28(1-12)-like immunoreactivity was measured in extracts of rat hypophysial portal blood and peripheral blood. The concentration of somatostatin-28(1-12) was higher in portal than in peripheral extracts, and its release into portal vessel blood was increased 4- to 5-fold by electrical stimulation of the median eminence. These results show that somatostatin-28(1-12) may be a physiological neurohormone and/or neurotransmitter.

摘要

在大鼠垂体门脉血和外周血的提取物中测量了生长抑素-28(1-12)样免疫反应性。垂体门脉血中生长抑素-28(1-12)的浓度高于外周提取物中的浓度，通过电刺激正中隆起，其向门脉血管血中的释放增加了4至5倍。这些结果表明，生长抑素-28(1-12)可能是一种生理性神经激素和/或神经递质。