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对泰晤士河西北地区归因于疫苗接种的疾病进行的为期7年的调查。

A 7-year survey of disorders attributed to vaccination in North West Thames region.

作者信息

Pollock T M, Morris J

出版信息

Lancet. 1983 Apr 2;1(8327):753-7. doi: 10.1016/s0140-6736(83)92037-8.

DOI:10.1016/s0140-6736(83)92037-8
PMID:6132093
Abstract

Voluntary reporting of vaccine reactions was intensified in a single large region for 7 years Anaphylaxis and collapse, convulsion, and neurological disorder were reported most frequently after diphtheria/tetanus/pertussis (DTP). The greater frequency of recorded reactions after DTP than after DT could have been due to bias caused by the adverse publicity accorded to pertussis vaccine, since no major difference was found when the immunisation histories of children admitted to hospital with such conditions were compared. No convincing evidence that DTP caused major neurological damage emerged from this large and lengthy study.

摘要

在一个大区域内加强了7年的疫苗反应自愿报告。白喉/破伤风/百日咳(DTP)疫苗接种后,过敏反应、虚脱、惊厥和神经紊乱的报告最为频繁。DTP疫苗接种后记录的反应比DT疫苗接种后更为频繁,这可能是由于百日咳疫苗受到的负面宣传所导致的偏差,因为对因这些情况入院的儿童的免疫史进行比较时,未发现重大差异。这项大规模且长期的研究没有得出令人信服的证据表明DTP疫苗会导致重大神经损伤。

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