Noya G, Dettori G, Muscas A, Spirito R, Niolu P, Marongiu G, Biglioli P
Minerva Med. 1983 Apr 7;74(14-15):787-90.
A double blind test with cimetidine and ranitidine conducted on 60 patients with acid reflux oesophagitis revealed cimetidine to be the more effective. Its success is felt to lie more in the drug's ability to activate defensive factors than in its inhibition of acid secretion.
对60例反流性食管炎患者进行的西咪替丁和雷尼替丁双盲试验表明,西咪替丁疗效更佳。人们认为其成功更多在于该药物激活防御因子的能力,而非抑制胃酸分泌的能力。