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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Horowitz M, Argov D, Mizrahi R

Comp Biochem Physiol A Comp Physiol. 1983;74(4):945-9. doi: 10.1016/0300-9629(83)90374-2.

Adaptation of salivary cooling mechanism during acclimation to heat (34 degrees C) and its role in thermoregulation of the rats was studied on conscious rats with either one submaxillary gland chronically cannulated or both submaxillaries ligated. 2. During heat stress (40 degrees C) acclimated rats showed a decrease both in rectal temperature threshold for salivation (Tre-TS), in salivary flow rate and in Tre (hyperthermic plateau). Animals survived for extended periods and rats with ligated glands survived 40% less than non-ligated rats. 3. For both cannulated and ligated rats short term acclimation (5 days) was the most effective. 4. It is suggested that earlier activation of salivation mechanism is associated with the decreased hyperthermic plateau and that the decreased salivary flow rate allows better control of water balance of the animals. Consequently, survival period during heat stress is extended.

研究了在适应热环境（34摄氏度）过程中唾液冷却机制的适应性及其在大鼠体温调节中的作用，实验对象为清醒大鼠，一部分大鼠一侧下颌下腺长期插管，另一部分大鼠双侧下颌下腺结扎。2. 在热应激（40摄氏度）期间，适应热环境的大鼠唾液分泌的直肠温度阈值（Tre - TS）、唾液流速和Tre（热高原）均下降。动物存活时间延长，腺体结扎的大鼠比未结扎的大鼠存活时间少40%。3. 对于插管和结扎的大鼠，短期适应（5天）最为有效。4. 研究表明，唾液分泌机制的早期激活与热高原降低有关，唾液流速降低有助于更好地控制动物的水平衡。因此，热应激期间的存活期得以延长。

Horowitz M, Argov D, Mizrahi R

Comp Biochem Physiol A Comp Physiol. 1983;74(4):945-9. doi: 10.1016/0300-9629(83)90374-2.

Adaptation of salivary cooling mechanism during acclimation to heat (34 degrees C) and its role in thermoregulation of the rats was studied on conscious rats with either one submaxillary gland chronically cannulated or both submaxillaries ligated. 2. During heat stress (40 degrees C) acclimated rats showed a decrease both in rectal temperature threshold for salivation (Tre-TS), in salivary flow rate and in Tre (hyperthermic plateau). Animals survived for extended periods and rats with ligated glands survived 40% less than non-ligated rats. 3. For both cannulated and ligated rats short term acclimation (5 days) was the most effective. 4. It is suggested that earlier activation of salivation mechanism is associated with the decreased hyperthermic plateau and that the decreased salivary flow rate allows better control of water balance of the animals. Consequently, survival period during heat stress is extended.

研究了在适应热环境（34摄氏度）过程中唾液冷却机制的适应性及其在大鼠体温调节中的作用，实验对象为清醒大鼠，一部分大鼠一侧下颌下腺长期插管，另一部分大鼠双侧下颌下腺结扎。2. 在热应激（40摄氏度）期间，适应热环境的大鼠唾液分泌的直肠温度阈值（Tre - TS）、唾液流速和Tre（热高原）均下降。动物存活时间延长，腺体结扎的大鼠比未结扎的大鼠存活时间少40%。3. 对于插管和结扎的大鼠，短期适应（5天）最为有效。4. 研究表明，唾液分泌机制的早期激活与热高原降低有关，唾液流速降低有助于更好地控制动物的水平衡。因此，热应激期间的存活期得以延长。