D'Ermo F, Secchi A G, Mancini B, Fregona I
Ophthalmologica. 1977;176(3):164-9. doi: 10.1159/000308710.
Normal rabbit lenses exposed in vitro to heterologous antibody (Ab)--antigen (Ag) interactions lose control of the intracellular 86Rb; this membrane damage, which seems to be related to the quantitative ratio Ab/Ag, is relatively complement independent and is followed by a subsequent leakage of lenticular proteins. A possible implication of these findings in the development of complicated cataracts in uveitis (as 'permeability cataracts') and in the self-maintenance of recurrent uveal inflammation is shortly discussed.
体外暴露于异源抗体（Ab）-抗原（Ag）相互作用的正常兔晶状体失去对细胞内86Rb的控制；这种膜损伤似乎与Ab/Ag的定量比例有关，相对不依赖补体，随后会出现晶状体蛋白的泄漏。本文简要讨论了这些发现对葡萄膜炎并发白内障（如“通透性白内障”）发展以及复发性葡萄膜炎症自我维持的可能影响。
