Sigurdsson J A, Bengtsson C
Acta Med Scand. 1983;213(3):183-90.
Altogether 1462 middle-aged women aged 38-60 participated in a population study which was carried out in Göteborg, Sweden in 1968-69. Of these women, 1302 were re-investigated six years later in a follow-up study. Studied cross-sectionally, headache and nycturia were found to be more common in both untreated and treated hypertensives than in a non-hypertensive reference group. The prevalences of headache seemed to be U-shaped when related to the BP levels, with the highest prevalences in the lowest and highest quintiles of BP levels. In the longitudinal study, headache did not occur more often in those women who had started antihypertensive treatment than in the others. Dizziness as a new symptom occurred more often in women who had started to take antihypertensive drugs than in those who had not, and was more common in those who had started taking diuretics than in those starting on beta-blockers. The prevalences of eyeground phenomena and ECG changes seemed to increase linearly with increasing BP levels. It is concluded that some symptoms and signs are related to BP levels, and some of the symptoms in hypertensive women may also be related to antihypertensive treatment as such and to the type of antihypertensive treatment given.
共有1462名年龄在38至60岁之间的中年女性参与了一项于1968年至1969年在瑞典哥德堡进行的人群研究。在这些女性中，六年后有1302名女性在一项随访研究中接受了再次调查。横断面研究发现，无论是未治疗还是已治疗的高血压患者，头痛和夜尿症都比非高血压参照组更为常见。当与血压水平相关时，头痛的患病率似乎呈U形，在血压水平最低和最高的五分位数中患病率最高。在纵向研究中，开始接受降压治疗的女性头痛发生频率并不比其他女性更高。头晕作为一种新症状，在开始服用降压药的女性中比未服用降压药的女性更常出现，并且在开始服用利尿剂的女性中比开始服用β受体阻滞剂的女性更常见。眼底现象和心电图改变的患病率似乎随着血压水平的升高而呈线性增加。得出的结论是，一些症状和体征与血压水平有关，高血压女性的一些症状也可能与降压治疗本身以及所给予的降压治疗类型有关。
