沙蚕体腔液中的血凝素活性。

Hemagglutinin activity in Nereis coelomic fluid.

Russell C S, Rodriguez J, Lai P S

Comp Biochem Physiol A Comp Physiol. 1983;75(1):57-64. doi: 10.1016/0300-9629(83)90044-0.

Abstract

Nereis coelomic fluid agglutinates rat, mouse, chicken, guinea pig and rhesus monkey erythrocytes (RBC). 2. Lipid fractions of the particulate matter from coelomic fluid are hemagglutinins exhibiting different activity inhibition profiles with complex polysaccharides. 3. The high mol. wt hemagglutinin from coelomic fluid supernatant is not a protein and is inhibited by bovine submaxillary mucin (BSM), thyroglobulin, transferrin and their asialo derivatives. 4. Coelomic fluid supernatant has a population of low mol. wt protein hemagglutinins inhibited by BSM, fetuin, antiserum to coelomic fluid and some mannan preparations. 5. Hemagglutination by lipids characterized by RBC specificity and specificity for inhibition by carbohydrate is noteworthy and may be significant in studies of cellular interactions and immunity in invertebrates.

摘要

沙蚕体腔液能凝集大鼠、小鼠、鸡、豚鼠和恒河猴的红细胞（RBC）。2. 体腔液中颗粒物质的脂质部分是血凝素，对复合多糖表现出不同的活性抑制谱。3. 体腔液上清液中的高分子量血凝素不是蛋白质，可被牛颌下粘蛋白（BSM）、甲状腺球蛋白、转铁蛋白及其去唾液酸衍生物抑制。4. 体腔液上清液中有一群低分子量蛋白质血凝素，可被BSM、胎球蛋白、体腔液抗血清和一些甘露聚糖制剂抑制。5. 以红细胞特异性和碳水化合物抑制特异性为特征的脂质血凝作用值得关注，可能在无脊椎动物细胞相互作用和免疫研究中具有重要意义。