Bucke B, Distler H J, Schoyerer R, Willner W
Fortschr Med. 1983 Mar 24;101(11):494-6.
63 patients were treated with the combination of pseudoephedrine hydrochloride and triprolidine hydrochloride (Actifed). Indications were infectious, allergic and vasomotoric rhinitis. The 63 patients divided in 32 children in the age of 2 to 12 years and 31 adults in the age of 14 to 56 years. The daily dose range depending on age was 90.0 to 180.0 mg pseudoephedrine hydrochloride and 3.75 to 7.5 mg triprolidine hydrochloride, applicated either as syrup or as tablets. All patients accepted the drug well. In 58 cases the effect of the drug for treatment of common cold was very good and good. Side-effects were not observed, apart from tiredness in 18 cases, which--however--did only occur at the first day of treatment.
63名患者接受了盐酸伪麻黄碱和盐酸曲普利啶(复方盐酸伪麻黄碱缓释胶囊)联合治疗。适应症为感染性、过敏性和血管运动性鼻炎。这63名患者分为两组,32名年龄在2至12岁的儿童和31名年龄在14至56岁的成年人。根据年龄,每日剂量范围为盐酸伪麻黄碱90.0至180.0毫克和盐酸曲普利啶3.75至7.5毫克,以糖浆或片剂形式服用。所有患者对该药物耐受性良好。58例患者治疗普通感冒的效果非常好或良好。除18例患者出现疲劳外,未观察到副作用,不过疲劳仅在治疗第一天出现。