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特非那定及其各成分治疗变应性鼻炎的双盲对照评价

A double-blind controlled evaluation of Actifed and its individual constituents in allergic rhinitis.

作者信息

Connell J T, Williams B O, Allen S, Cato A, Perkins J G

出版信息

J Int Med Res. 1982;10(5):341-7. doi: 10.1177/030006058201000505.

DOI:10.1177/030006058201000505
PMID:6128282
Abstract

Pseudoephedrine and triprolidine, administered every 6 hours as a combination, made separate and distinct contributions to the treatment of allergic rhinitis. Furthermore, the combination was perceived by the patients as being clinically superior to either of its components or placebo.

摘要

伪麻黄碱和曲普利啶联合使用，每6小时给药一次，对过敏性鼻炎的治疗分别有显著作用。此外，患者认为该组合在临床上优于其任何一种成分或安慰剂。

相似文献

1
A double-blind controlled evaluation of Actifed and its individual constituents in allergic rhinitis.特非那定及其各成分治疗变应性鼻炎的双盲对照评价
J Int Med Res. 1982;10(5):341-7. doi: 10.1177/030006058201000505.
2
An evaluation of triprolidine and pseudoephedrine in the treatment of allergic rhinitis.
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A Double-blind crossover trial of pseudoephedrine and triprolidine, alone and in combination, for the treatment of allergenic rhinitis.
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[Double blind crossover study of pseudoephedrine and triprolidine alone and in combination in the treatment of allergic rhinitis (author's transl)].伪麻黄碱与曲普利啶单独及联合治疗变应性鼻炎的双盲交叉研究（作者译）
Prensa Med Mex. 1975 Nov-Dec;40(11-12):383-8.
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[Rhinitis therapy. Experiences with triprolidine hydrochloride/pseudoephedrin hydrochloride, a decongestive and antiallergic therapeutic agent].[鼻炎治疗。使用盐酸曲普利啶/盐酸伪麻黄碱（一种减充血和抗过敏治疗剂）的经验]
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Comparison of pseudoephedrine and triprolidine, alone and in combination in preventing nasal congestion in subjects with allergic rhinitis using nasal histamine challenge.使用鼻腔组胺激发试验比较伪麻黄碱和曲普利啶单独及联合使用对变应性鼻炎患者鼻充血的预防作用。
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Acrivastine/pseudoephedrine (Semprex-D) for seasonal allergic rhinitis.阿伐斯汀/伪麻黄碱（仙特明-D）用于季节性变应性鼻炎。
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Onset-of-action for antihistamine and decongestant combinations during an outdoor challenge.户外激发试验中抗组胺药和解充血药组合的起效时间。
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引用本文的文献

1
Development and evaluation of a novel modified-release pellet-based tablet system for the delivery of loratadine and pseudoephedrine hydrochloride as model drugs.开发和评价一种新型的基于缓释微丸的片剂系统，用于洛他定和盐酸伪麻黄碱作为模型药物的传递。
AAPS PharmSciTech. 2010 Jun;11(2):910-6. doi: 10.1208/s12249-010-9456-2. Epub 2010 May 22.
2
Comparison of pseudoephedrine and triprolidine, alone and in combination in preventing nasal congestion in subjects with allergic rhinitis using nasal histamine challenge.使用鼻腔组胺激发试验比较伪麻黄碱和曲普利啶单独及联合使用对变应性鼻炎患者鼻充血的预防作用。
Br J Clin Pharmacol. 1984 Jul;18(1):86-9. doi: 10.1111/j.1365-2125.1984.tb05026.x.
3
Effects of terfenadine and pseudoephedrine, alone and in combination in a nasal provocation test and in perennial rhinitis.
特非那定和伪麻黄碱单独及联合应用于鼻激发试验和常年性鼻炎的效果。
Eur J Clin Pharmacol. 1991;41(4):321-4. doi: 10.1007/BF00314960.