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去甲氯氮卓是否具有特定的抗性欲作用?五项观察报告。

Does chlordesmethyldiazepam have a specific anti-erotic effect? Report on five observations.

作者信息

Cocchi R, Passanisi S, Macci F

出版信息

Acta Psychiatr Belg. 1982;82(6):555-64.

PMID:6134427
Abstract

Five observations in adult subjects (4 female, 1 male) in which the administration of chlordesmethyldiazepam (2-4 mg/day) alone, or in association with other psychodrugs has demonstrated a specific anti-erotic action, with a short therapeutic latency period, reversible, and not found in other benzodiazepines (chlordiazepoxide, diazepam, lorazepam, flunitrazepam, prazepam) which the patients had previously taken, are presented in detail. One of the cases was diagnosed with Clérambault Syndrome of seven years' duration [Acta psychiat. belg., 82, 555-564 (1982)].

摘要

详细介绍了5例成年受试者(4名女性,1名男性)的情况,单独给予去甲氯氮卓(2 - 4毫克/天)或与其他精神药物联合使用时,均显示出特定的抗性欲作用,治疗潜伏期短,作用可逆,且在患者之前服用过的其他苯二氮卓类药物(氯氮卓、地西泮、劳拉西泮、氟硝西泮、普拉西泮)中未发现这种情况。其中1例被诊断为持续7年的克莱朗博综合征[《比利时精神病学学报》,82, 555 - 564(1982)]。

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Does chlordesmethyldiazepam have a specific anti-erotic effect? Report on five observations.去甲氯氮卓是否具有特定的抗性欲作用?五项观察报告。
Acta Psychiatr Belg. 1982;82(6):555-64.
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Double-blind placebo cross-over study of long-acting (chlordesmethyldiazepam) versus short-acting (lorazepam) benzodiazepines in generalized anxiety disorders.长效(氯地西泮)与短效(劳拉西泮)苯二氮䓬类药物治疗广泛性焦虑症的双盲安慰剂交叉研究。
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The psychosedative effect of chlordesmethyldiazepam on anxiety states in neurotic and psychotic inpatients.去甲氯氮卓对神经症和精神病住院患者焦虑状态的精神镇静作用。
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Double-blind cross-over clinical comparison of two 2'-chloro benzodiazepines: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one (chlordesmethyldiazepam) versus 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one (lorazepam) in neurotic anxiety.两种2'-氯苯二氮䓬类药物的双盲交叉临床比较:7-氯-5-(2-氯苯基)-1,3-二氢-2H-1,4-苯并二氮杂䓬-2-酮(去甲氯氮卓)与7-氯-5-(邻氯苯基)-1,3-二氢-3-羟基-2H-1,4-苯并二氮杂䓬-2-酮(劳拉西泮)治疗神经症性焦虑的比较
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