Sriwatanakul K, Weis O F, Alloza J L, Kelvie W, Weintraub M, Lasagna L
JAMA. 1983 Aug 19;250(7):926-9.
We reviewed 526 medical records of surgical patients and interviewed 81 of these patients. We also sent questionnaires to house staff (57 of 97 responded) and nurses (70 of 142 responded) involved in the care of these patients. A substantial number of patients suffered at least moderate pain during the postoperative period despite analgesic medication. Patients received 70% of the maximal ordered analgesic dose in the first 24 hours. Physicians prescribed drugs in doses that were often inadequate and to be given at inflexible intervals. The optimal doses and duration of action of meperidine, as judged by the house staff and nurses, did not agree with the accepted pharmacologic profile of this drug.
我们查阅了526份外科手术患者的病历,并对其中81名患者进行了访谈。我们还向参与这些患者护理的住院医生(97人中有57人回复)和护士(142人中有70人回复)发放了问卷。尽管使用了镇痛药物,但仍有相当数量的患者在术后至少遭受中度疼痛。患者在术后头24小时内仅接受了最大医嘱镇痛剂量的70%。医生所开药物的剂量往往不足,且给药间隔固定不变。住院医生和护士判断的哌替啶最佳剂量和作用持续时间与该药物公认的药理学特征不符。