Deniker P
Acta Psychiatr Belg. 1983 May-Jun;83(3):239-54.
The contributions made by various stages of psychopharmacology - i.e. pharmacotherapy of psychoses as well as experimental psychiatry - towards the understanding of the structure and nature of major psychoses are considered. The various types of antipsychotic agents (neuroleptics, antidepressants and lithium) are reviewed as well as their characteristics, classification and biochemical properties. Besides, pharmacopsychoses resulting from heavy and repeated abuse of hallucinatory and other drugs are put forward as a model worthy of further studies. This paper concludes by an appeal for a truly multidisciplinary collaboration in order for modern biologic psychiatry to progress.
本文探讨了精神药理学的各个阶段——即精神病的药物治疗以及实验精神病学——对理解主要精神病的结构和本质所做的贡献。文中回顾了各类抗精神病药物(抗精神病药、抗抑郁药和锂盐)及其特点、分类和生化特性。此外,还提出了因大量反复滥用致幻剂和其他药物导致的药源性精神病,作为一个值得进一步研究的模型。本文最后呼吁开展真正的多学科合作,以使现代生物精神病学取得进展。