Spano J S, August J R, Henderson R A, Dumas M B, Groth A H
Am J Vet Res. 1983 Nov;44(11):2049-53.
Activities of serum gamma-glutamyl transpeptidase (GGT), alkaline phosphatase (ALP), and alanine aminotransferase (ALT) were determined in healthy cats and in cats before and after treatment: common bile duct ligation, carbon tetrachloride administration, sham surgery, or anesthesia only. Significant (P less than 0.01) increases in serum GGT, ALP, and ALT occurred in cats with ligated bile ducts. Significant (P less than 0.01) increases in serum ALT occurred in carbon tetrachloride-treated cats. Increases of serum GGT, ALP, or ALT were not observed in cats subjected to sham surgery or anesthesia only compared with these cats' baseline values and values in healthy cats. Tissue GGT activity was measured in liver, renal cortex, jejunal mucosa, and bile ducts. There was a 1.5-fold increase in GGT activity in livers of cats with ligated bile ducts, compared with that in livers of healthy cats.
测定了健康猫以及接受治疗前后的猫（进行胆总管结扎、给予四氯化碳、假手术或仅麻醉）血清γ-谷氨酰转肽酶（GGT）、碱性磷酸酶（ALP）和丙氨酸氨基转移酶（ALT）的活性。胆总管结扎的猫血清GGT、ALP和ALT显著（P<0.01）升高。四氯化碳处理的猫血清ALT显著（P<0.01）升高。与这些猫的基线值以及健康猫的值相比，仅接受假手术或麻醉的猫未观察到血清GGT、ALP或ALT升高。测量了肝脏、肾皮质、空肠黏膜和胆管的组织GGT活性。与健康猫的肝脏相比，胆总管结扎的猫肝脏中GGT活性增加了1倍。
