Gualtieri C T, Quade D, Hicks R E, Mayo J P, Schroeder S R
Am J Psychiatry. 1984 Jan;141(1):20-3. doi: 10.1176/ajp.141.1.20.
Of 41 children, adolescents, and young adults who were withdrawn from chronic neuroleptic treatment, 18 developed tardive dyskinesia, withdrawal dyskinesia, nondyskinetic withdrawal symptoms, or transient behavior deterioration. Development of neuroleptic-related problems seemed to be associated with cumulative neuroleptic dose and possibly with the sex of the subject. Only 12 of the 41 subjects required resumption of neuroleptic treatment after a prolonged trial withdrawal period.
在41名停止慢性抗精神病药物治疗的儿童、青少年和青年中，18人出现了迟发性运动障碍、撤药运动障碍、无运动障碍的撤药症状或短暂行为恶化。抗精神病药物相关问题的出现似乎与抗精神病药物的累积剂量有关，也可能与受试者的性别有关。在经过长时间的停药试验期后，41名受试者中只有12人需要恢复抗精神病药物治疗。
