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奥地利医疗卫生服务中作为职业病的乙型肝炎的流行病学及风险计算

Epidemiology and risk calculation of hepatitis-B as an occupational disease in the Austrian health service.

作者信息

Maruna H, Westphal G

出版信息

Int Arch Occup Environ Health. 1986;57(4):259-65. doi: 10.1007/BF00406182.

DOI:10.1007/BF00406182
PMID:3086237
Abstract

The present investigation of occupation-related cases of hepatitis in the statistics of occupational diseases attempted to quantify the specific risk of this infectious disease for all occupations within the health service. The absolute number of occupation-related cases of hepatitis B increased fourfold over the last two decades, while at the same time the number of health service employees only doubled. In comparison with the Austrian population, the hepatitis risk is about 11 times higher for the health service employees. Especially laboratory personnel, doctors and support service personnel are exposed to these increased risks. The relative risks according to age, sex and type of occupation were also investigated and a comparison was made with the findings of other investigations in Austrian and international specialized literature. First information is also given about the findings of the screening on immunity against HBs-antigen, anti-HBs and anti-HBc in the professional group of health service employees. The calculations, and also experience in other countries, show the need for the introduction of an active protective immunization against hepatitis B for all health service employees. The prophylaxis against hepatitis that was begun in Austria on January 1st, 1983, is the first extensive vaccination programme against this liver disease, that on the basis of research done by a social security institute, has been implemented free of charge by this institute for a professional category.

摘要

本次对职业病统计中与职业相关的肝炎病例的调查,试图量化这种传染病对卫生服务行业内所有职业的具体风险。在过去二十年中,与职业相关的乙型肝炎病例绝对数增加了四倍,而与此同时,卫生服务行业员工数量仅翻了一番。与奥地利总人口相比,卫生服务行业员工感染肝炎的风险约高11倍。特别是实验室人员、医生和辅助服务人员面临着这些更高的风险。还调查了按年龄、性别和职业类型划分的相对风险,并与奥地利和国际专业文献中其他调查结果进行了比较。还首次提供了卫生服务行业员工专业组中乙肝表面抗原、乙肝表面抗体和乙肝核心抗体免疫筛查的结果。计算结果以及其他国家的经验表明,有必要为所有卫生服务行业员工开展积极的乙肝保护性免疫接种。1983年1月1日在奥地利开始的肝炎预防措施,是首个针对这种肝病的大规模疫苗接种计划,该计划基于一家社会保障机构的研究,由该机构为一个职业类别免费实施。

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本文引用的文献

1
Hepatitis B infection in hospital personnel during an eight-year period; policies for screening and pregnancy in high risk areas.八年间医院工作人员的乙肝感染情况;高风险地区的筛查及妊娠相关政策
Am J Med. 1981 Apr;70(4):924-7. doi: 10.1016/0002-9343(81)90557-x.
2
Hepatitis B vaccine: demonstration of efficacy in a controlled clinical trial in a high-risk population in the United States.乙肝疫苗:在美国高危人群的对照临床试验中疗效的证明
N Engl J Med. 1980 Oct 9;303(15):833-41. doi: 10.1056/NEJM198010093031501.
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[Hepatitis B contamination of Viennese hospital personnel].
[维也纳医院工作人员的乙型肝炎感染情况]
Wien Klin Wochenschr. 1983 Apr 1;95(7):235-40.
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[Iatrogenic and environmentally induced diseases of the liver in old age: viral hepatitis in old age].[老年医源性和环境性肝病:老年病毒性肝炎]
Aktuelle Gerontol. 1983 Nov;13(6):214-6.
5
Randomised placebo-controlled trial of hepatitis B surface antigen vaccine in french haemodialysis units: II, Haemodialysis patients.法国血液透析单位中乙型肝炎表面抗原疫苗的随机安慰剂对照试验:II,血液透析患者
Lancet. 1981 Apr 11;1(8224):797-800. doi: 10.1016/s0140-6736(81)92679-9.
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Letter: HBAg in breast milk.信件:母乳中的乙肝表面抗原。
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7
Risk factors in transmission of non-A, non-B posttransfusion hepatitis. The role of hepatitis B antibody in donor blood.非甲非乙型输血后肝炎传播的危险因素。献血者血液中乙肝抗体的作用。
Transfusion. 1977 Nov-Dec;17(6):579-85. doi: 10.1046/j.1537-2995.1977.17678075654.x.