普罗替林光照射产物的结构解析
Structure elucidation of protriptyline photoirradiation products.
作者信息
Jones G E, Sharples D
出版信息
J Pharm Pharmacol. 1984 Jan;36(1):46-8. doi: 10.1111/j.2042-7158.1984.tb02986.x.
Abstract
Three photoirradiation products of the tricyclic antidepressant protriptyline have been isolated by preparative tlc and identified as the 10,11-epoxide, 10-hydroxy and 10,11-dihydrodiol derivatives of protriptyline by tlc, uv and mass spectroscopy.
摘要
通过制备薄层层析法分离出三环类抗抑郁药普罗替林的三种光辐照产物，并通过薄层层析法、紫外光谱法和质谱法将其鉴定为普罗替林的10,11-环氧化物、10-羟基和10,11-二氢二醇衍生物。
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