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[磷霉素。I. 体外抗菌作用]

[Fosfomycin. I. Antimicrobial action in vitro].

作者信息

Carlone N A, Cuffini A M, Cattaneo O

出版信息

G Batteriol Virol Immunol. 1977 Jan-Jun;70(1-6):100-7.

PMID:614140
Abstract

The results obtained from the test of the in vitro activity of Fosfomycin by a concentration of 104 bacteria/ml and by Nutrient Broth with 5% defibrinated blood, have shown that the drug has a capacity of action on both Gram-negative and Gram-positive germs, also on beta-lactamase producing bacteria. Fosfomycin is a bactericidal antibiotic. infact the M.I.C. values are simjlar to M.B.C. values.

摘要

以每毫升104个细菌的浓度在含5%去纤维蛋白血的营养肉汤中对磷霉素进行体外活性测试,结果表明该药物对革兰氏阴性菌和革兰氏阳性菌均有作用,对产β-内酰胺酶的细菌也有作用。磷霉素是一种杀菌性抗生素。事实上,其最低抑菌浓度(MIC)值与最低杀菌浓度(MBC)值相似。

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