Holloway D A, Heath A G
Comp Biochem Physiol A Comp Physiol. 1984;77(2):267-73. doi: 10.1016/0300-9629(84)90059-8.
Tidal volume, respiratory frequency, and minute volume were measured with total body plethysmography. Both hypercapnic (0-7% CO2) and hypoxic (13-21% O2) gas mixtures caused "dose" related hyperventilation in the hamsters. However, there was no synergism between combined stimuli. Rats exhibited greater hyperventilation than the hamsters during hypercapnic + hypoxic and hypercapnic exposures. Hamsters responded more than the rats to hypoxia alone. Greater blood buffering capacity of hamsters is a possible explanation for the species differences in ventilatory sensitivity.
采用全身体积描记法测量潮气量、呼吸频率和分钟通气量。高碳酸血症（0 - 7%二氧化碳）和低氧血症（13 - 21%氧气）的混合气体均导致仓鼠出现“剂量”相关的通气过度。然而，联合刺激之间不存在协同作用。在高碳酸血症 + 低氧血症和高碳酸血症暴露期间，大鼠表现出比仓鼠更强的通气过度。仓鼠对单独低氧的反应比大鼠更明显。仓鼠具有更强的血液缓冲能力可能是通气敏感性存在物种差异的一个解释。
