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α受体阻滞剂和β受体阻滞剂对豚鼠胃酸分泌的影响。

The effect of alpha- and beta-receptor blocking agents on gastric acid secretion in guinea-pigs.

作者信息

Gauperaa T, Green A R, Johnson J A

出版信息

Scand J Gastroenterol. 1983 Mar;18(2):313-6. doi: 10.3109/00365528309181599.

DOI:10.3109/00365528309181599
PMID:6143394
Abstract

The effects of alpha- and beta-receptor blocking agents on gastric acid secretion were tested on 95 female guinea-pigs. Alpha blockade insignificantly inhibited the gastric acid secretion in the unstimulated animals, whereas in those stimulated with histamine, significant reduction was seen. Beta blockade had no influence on gastric secretion in the unstimulated animals but significantly enhanced the histamine-stimulated secretion of acid.

摘要

在95只雌性豚鼠身上测试了α受体阻滞剂和β受体阻滞剂对胃酸分泌的影响。α受体阻滞对未受刺激的动物胃酸分泌的抑制作用不显著,而在组胺刺激的动物中,胃酸分泌则显著减少。β受体阻滞对未受刺激动物的胃酸分泌没有影响,但显著增强了组胺刺激的胃酸分泌。

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