• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠慢性镁缺乏所致恶性T细胞淋巴瘤的酶组织化学

Enzyme histochemistry of malignant T cell lymphoma due to chronic magnesium deficiency in rats.

作者信息

Gossrau R, Vormann J, Günther T

出版信息

Histochemistry. 1984;80(2):183-6. doi: 10.1007/BF00679994.

DOI:10.1007/BF00679994
PMID:6143741
Abstract

The lymphocytes of the rat thymus can be grossly differentiated by their cell membrane-bound proteinases. Subcapsular thymocytes lack aminopeptidase A (APA) and AMP and gamma-glutamyltranspeptidase (GGT). Cortical thymocytes show a high activity of APA but no APM and no GGT. Medullar thymocytes possess a high GGT and APM activity but are free of APA. Under Mg deficiency, the APA-negative subcapsular thymocytes are reduced. In lymphoma and beginning lymphoma, APA, APM and GGT are absent. In lymphoma, the alkaline phosphatase activity is increased. Differences are found for dipeptidylpeptidase IV (DPP IV). In some lymphoma, its activity is reduced, in others the DPP IV activity is increased.

摘要

大鼠胸腺中的淋巴细胞可通过其细胞膜结合蛋白酶进行大致区分。被膜下胸腺细胞缺乏氨肽酶A(APA)、AMP和γ-谷氨酰转肽酶(GGT)。皮质胸腺细胞显示出高活性的APA,但没有APM和GGT。髓质胸腺细胞具有高活性的GGT和APM,但没有APA。在镁缺乏的情况下,APA阴性的被膜下胸腺细胞会减少。在淋巴瘤和早期淋巴瘤中,不存在APA、APM和GGT。在淋巴瘤中,碱性磷酸酶活性增加。二肽基肽酶IV(DPP IV)存在差异。在一些淋巴瘤中,其活性降低,而在另一些淋巴瘤中,DPP IV活性增加。

相似文献

1
Enzyme histochemistry of malignant T cell lymphoma due to chronic magnesium deficiency in rats.大鼠慢性镁缺乏所致恶性T细胞淋巴瘤的酶组织化学
Histochemistry. 1984;80(2):183-6. doi: 10.1007/BF00679994.
2
Histochemistry of some proteases in the normal rabbit, pig and ox corneas.正常兔、猪和牛角膜中某些蛋白酶的组织化学研究
Histochemistry. 1986;84(1):67-71. doi: 10.1007/BF00493423.
3
Enzymatic and morphological response of the thymus to drugs in normal and zinc-deficient pregnant rats and their fetuses.
Histochemistry. 1987;86(3):321-9. doi: 10.1007/BF00490266.
4
Histochemical demonstration of peptidases in the human kidney.人肾脏中肽酶的组织化学显示
Histochemistry. 1985;83(4):337-41. doi: 10.1007/BF00684380.
5
Assay of apical membrane enzymes based on fluorogenic substrates.基于荧光底物的顶端膜酶检测。
Anal Biochem. 1992 Feb 1;200(2):352-8. doi: 10.1016/0003-2697(92)90478-p.
6
[Distribution of the activity of some peptidases in the pancreas of human embryo].
Acta Univ Palacki Olomuc Fac Med. 1991;131:137-43.
7
Histochemical study of aminopeptidase M, aminopeptidase A, and gamma-glutamyltransferase in the nasal cavity of laboratory rodents andman.
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove. 1994;37(1):13-7.
8
Alkaline phosphatase and gamma glutamyltranspeptidase in human lymphomas.人淋巴瘤中的碱性磷酸酶和γ-谷氨酰转肽酶
Tumori. 1986 Feb 28;72(1):71-4. doi: 10.1177/030089168607200110.
9
Developmental changes of enzymes involved in peptide degradation in isolated rat brain microvessels.
Peptides. 1994;15(6):1085-8. doi: 10.1016/0196-9781(94)90074-4.
10
A monoclonal antibody detecting dipeptidylpeptidase IV in human tissue.
Virchows Arch A Pathol Anat Histopathol. 1986;409(2):263-73. doi: 10.1007/BF00708333.

引用本文的文献

1
Cytochemistry of membrane proteases.膜蛋白酶的细胞化学
Histochem J. 1985 Jul;17(7):737-71. doi: 10.1007/BF01003312.
2
Enzymatic and morphological response of the thymus to drugs in normal and zinc-deficient pregnant rats and their fetuses.
Histochemistry. 1987;86(3):321-9. doi: 10.1007/BF00490266.
3
Proteases and antiproteases: new trends in cytochemical research.
Histochem J. 1985 May;17(5):522-6. doi: 10.1007/BF01003179.

本文引用的文献

1
Epithelial lymphocytes in the epididymis and intestine.
Folia Morphol (Praha). 1980;28(1):123-5.
2
Development and properties of malignant lymphoma induced by magnesium deficiency in rats.大鼠缺镁诱导的恶性淋巴瘤的发生与特性
J Cancer Res Clin Oncol. 1982;104(1-2):63-73. doi: 10.1007/BF00402054.
3
Proteinases in pathology. Usefulness of histochemical methods.病理学中的蛋白酶。组织化学方法的实用性。
J Histochem Cytochem. 1981 Mar;29(3A Suppl):481-93. doi: 10.1177/29.3.481.
4
Investigation of proteinases in the digestive tract using 4-methoxy-2-naphthylamine (MNA) substrates.使用4-甲氧基-2-萘胺(MNA)底物对消化道中的蛋白酶进行研究。
J Histochem Cytochem. 1981 Mar;29(3A Suppl):464-80. doi: 10.1177/29.3.464.
5
Stepwise cleavage of the pro part of promelittin by dipeptidylpeptidase IV. Evidence for a new type of precursor--product conversion.二肽基肽酶IV对前蜂毒溶血肽原部分的逐步切割。一种新型前体-产物转化的证据。
Eur J Biochem. 1980 Oct;111(1):49-58. doi: 10.1111/j.1432-1033.1980.tb06073.x.
6
The sequential analysis of liver cancer induction.肝癌诱导的序贯分析。
Biochim Biophys Acta. 1980 May 6;605(2):149-66. doi: 10.1016/0304-419x(80)90002-5.
7
Cytochemical reactivity of T mu lymphocytes in human lymphatic tissue for dipeptidylaminopeptidase IV.人淋巴组织中Tμ淋巴细胞对二肽基氨基肽酶IV的细胞化学反应性。
Histochem J. 1982 Nov;14(6):889-95. doi: 10.1007/BF01005231.
8
Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase.酵母α因子是由一种更大的前体多肽加工而来:一种膜结合二肽基氨肽酶的重要作用。
Cell. 1983 Mar;32(3):839-52. doi: 10.1016/0092-8674(83)90070-3.
9
Membrane alterations in magnesium-deficiency-induced malignant T cell lymphoma.镁缺乏诱导的恶性T细胞淋巴瘤中的膜改变
Magnesium. 1984;3(1):29-37.
10
Delineation of membrane-bound phosphatase activities in normal and leukemic thymocytes.正常和白血病胸腺细胞中膜结合磷酸酶活性的描绘
Biochim Biophys Acta. 1983 Apr 20;756(3):385-94. doi: 10.1016/0304-4165(83)90349-5.