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宫颈腺癌中嗜银细胞肽类激素的免疫组化显示

Immunohistochemical demonstration of peptide hormones in cervical adenocarcinomas with argyrophil cells.

作者信息

Ueda G, Yamasaki M, Inoue M, Tanaka Y, Hiramatsu K, Inoue Y, Abe Y

出版信息

Int J Gynecol Pathol. 1984;2(4):373-9. doi: 10.1097/00004347-198404000-00005.

DOI:10.1097/00004347-198404000-00005
PMID:6144639
Abstract

Thirty patients with cervical adenocarcinoma were analyzed clinicopathologically with special reference to argyrophil cells. In contrast to argyrophil small cell carcinoma of the cervix, four adenocarcinomas with argyrophil cells were not more aggressive than the remaining 26 usual ones. One or two peptide hormones were demonstrated in three out of four tumors with argyrophil cells which were examined by immunohistochemistry. Somatostatin- and gastrin-containing cells were found in one tumor, but were located differently from each other. Either gastrin- or adrenocorticotropic hormone (ACTH)-containing cells were detected in two other tumors. They all corresponded to argyrophil cells, but were less numerous.

摘要

对30例宫颈腺癌患者进行了临床病理分析,特别关注亲银细胞。与宫颈亲银小细胞癌不同,4例含有亲银细胞的腺癌并不比其余26例常见腺癌更具侵袭性。在4例含有亲银细胞的肿瘤中,有3例通过免疫组织化学检测到一两种肽类激素。在1例肿瘤中发现了含生长抑素和胃泌素的细胞,但它们的位置彼此不同。在另外2例肿瘤中检测到含胃泌素或促肾上腺皮质激素(ACTH)的细胞。它们均与亲银细胞相对应,但数量较少。

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