Merté H J, Stryz J R
Klin Monbl Augenheilkd. 1984 Apr;184(4):316-7.
The results of a 3-month study of Befunolol eye drops 0.25% and 0.5% have already been published. The continuation of the study has shown that there is no diminution of the effect of the drug on IOP after a year of treatment. The absence of significant influences on pulse, systolic and diastolic blood pressure, corneal sensitivity, tear production, pupil diameter, visual acuity or visual field, which was established within the first 12 weeks, was also confirmed after 12 months.
0.25%和0.5%的倍他洛尔滴眼液为期3个月的研究结果已经发表。该研究的后续阶段表明,经过一年的治疗后,该药对眼压的疗效并未减弱。在最初12周内确定的对脉搏、收缩压和舒张压、角膜敏感性、泪液分泌、瞳孔直径、视力或视野无显著影响,在12个月后也得到了证实。