从一只大鼠的肿瘤标本中分离出肾综合征出血热（HFRS）病毒。
Isolation of hemorrhagic fever with renal syndrome (HFRS) virus from a tumor specimen in a rat.
作者信息
Yamanishi K, Dantas J R, Takahashi M, Yamanouchi T, Domae K, Kawamata J, Kurata T
出版信息
Biken J. 1983 Dec;26(4):155-60.
PMID:6146307
Abstract
A strain of hemorrhagic fever with renal syndrome (HFRS) virus was isolated in a cell culture from a tumor specimen in a rat kept in a medical institution in which there was a case of HFRS. Positive immunofluorescent reaction with sera from HFRS patients was recognized at the second passage and the number of cells containing antigen increased in the third passage. This virus, named B-1 strain, was identified as the HFRS virus by immunofluorescent tests with sera from patients.
摘要
在一家有肾综合征出血热（HFRS）病例的医疗机构饲养的大鼠的肿瘤标本中，通过细胞培养分离出一株HFRS病毒。在第二代传代时，观察到与HFRS患者血清的阳性免疫荧光反应，并且在第三代传代时含有抗原的细胞数量增加。这种病毒命名为B-1株，通过与患者血清进行免疫荧光试验鉴定为HFRS病毒。
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