Bateman N E, Uccellini D A
J Pharm Pharmacol. 1984 Jul;36(7):461-4. doi: 10.1111/j.2042-7158.1984.tb04426.x.
Formulation factors influencing vitamin bioavailability have been investigated, with vitamins A, E and B2, formulated in a new liquid vehicle (Aqua-Biosorb) and encapsulated into soft gelatin capsules, being compared with commercial formulations. There was an enhanced vitamin bioavailability from the new vehicle which appeared to be related to the surfactant system employed and the absence of vegetable oil in the formulation.
已对影响维生素生物利用度的制剂因素进行了研究,将以新型液体载体(水基生物吸附剂)配制并封装在软胶囊中的维生素A、E和B2与市售制剂进行了比较。新载体提高了维生素的生物利用度,这似乎与所采用的表面活性剂系统以及制剂中不含植物油有关。