Taskov M
Acta Physiol Pharmacol Bulg. 1977;3(4):53-7.
Crataemon contains the purified flavonoid mixture of Crataegus monogyna. Flowmetric studies of dog coronary blood flow show that it increases after intravenous application of 2 mg/kg crataemon. This increase is statistically significant and lasts about 30 min, with no significant changes in the heart rate and ECG. In experiments on cats it has been found that only the high crataemon doses have a bradycardic effect. Influence on the blood pressure is insignificant and brief. The minute cardiac volume and the cardiac index increase after all doses tested. The work of the left ventricle is also increased, which is considered to be favourable under conditions of operative shock. The general peripheral resistance is much less inhibited, most active being the highest dose tested.
山楂酮含有纯化的山楂黄酮混合物。对犬冠状动脉血流量的流量测定研究表明，静脉注射2mg/kg山楂酮后血流量增加。这种增加具有统计学意义，持续约30分钟，心率和心电图无明显变化。在猫的实验中发现，只有高剂量的山楂酮才有减慢心率的作用。对血压的影响不显著且短暂。所有测试剂量后每分心输出量和心脏指数均增加。左心室的作功也增加，这在手术性休克情况下被认为是有利的。总外周阻力受抑制程度小得多，测试的最高剂量最具活性。
