Hashimoto T
Neurol Res. 1984 Mar-Jun;6(1-2):22-8. doi: 10.1080/01616412.1984.11739659.
The pressure and flow patterns within intracranial aneurysms are little known. An investigation of intra-aneurysmal flow velocities was done on model glass and silastic aneurysms using a constant-temperature hot film anemometer (HFA) and a high frequency directional pulsed Doppler to measure flow velocities. Maximum turbulent flow occurred at the neck and minimum flow at the dome of aneurysms. The intra-aneurysmal flow behaved differently with different neck diameters and different volumes. Turbulent flow was more severe in broad neck aneurysms and those with a small volume, while maximum turbulent flow was demonstrated in small out-pouching aneurysms. Increased turbulent flow was also detected in loculated aneurysms and in those with thinner walls. The results suggested that the random turbulent forces may be a cause of out-pouching and enlargement at eroded or congenitally weak area of arterial walls. Enlargement occurs with further erosion of endothelial cells and the internal elastic membrane.
颅内动脉瘤内的压力和血流模式鲜为人知。使用恒温热膜风速仪（HFA）和高频定向脉冲多普勒对模型玻璃动脉瘤和硅橡胶动脉瘤进行了动脉瘤内血流速度的研究，以测量血流速度。最大湍流发生在动脉瘤颈部，而动脉瘤顶部的血流最小。动脉瘤内的血流在不同的颈部直径和不同的体积下表现不同。宽颈动脉瘤和小体积动脉瘤的湍流更严重，而小的外突型动脉瘤表现出最大的湍流。在分叶状动脉瘤和壁较薄的动脉瘤中也检测到湍流增加。结果表明，随机湍流力可能是动脉壁侵蚀或先天性薄弱区域出现外突和扩大的原因。随着内皮细胞和内弹性膜的进一步侵蚀，动脉瘤会扩大。
