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前列腺和前列腺尿道的内分泌旁分泌细胞:一项超微结构研究。

Endocrine-paracrine cells of the prostate and prostatic urethra: an ultrastructural study.

作者信息

di Sant'Agnese P A, De Mesy Jensen K L

出版信息

Hum Pathol. 1984 Nov;15(11):1034-41. doi: 10.1016/s0046-8177(84)80246-4.

DOI:10.1016/s0046-8177(84)80246-4
PMID:6149186
Abstract

A remarkable morphologic diversity among the endocrine-paracrine (EP) cells of the prostate and prostatic urethra was found in this study. Based on granule morphology, a wide variety of EP cell "types" was discerned, although many intermediate and mixed cells, forming a continuum, were also observed. The EP cells were of both the open (containing luminal borders) and closed types. The latter often had long dendritic processes. Prominent lamellar bodies, possibly representing a form of crinophagy, were present in some EP cells. The variety and morphologic complexity of these prostatic and urethral EP cells suggest that they play an important role in both normal and pathologic conditions.

摘要

本研究发现前列腺和前列腺尿道的内分泌旁分泌(EP)细胞存在显著的形态学多样性。基于颗粒形态,可识别出多种EP细胞“类型”,不过也观察到许多形成连续体的中间型和混合型细胞。EP细胞有开放型(含管腔边界)和封闭型两种。后者通常有长的树突状突起。一些EP细胞中存在显著的板层小体,可能代表一种自噬形式。这些前列腺和尿道EP细胞的多样性和形态复杂性表明它们在正常和病理状态下均发挥重要作用。

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