肌营养不良小鼠大脑中N-乙酰-L-天冬氨酸的减少。
Decrease in N-acetyl-L-aspartic acid in brain of myodystrophic mice.
作者信息
Marcucci F, Colombo L, De Ponte G, Mussini E
出版信息
J Neurochem. 1984 Nov;43(5):1484-6. doi: 10.1111/j.1471-4159.1984.tb05412.x.
Abstract
Brain tissue from myodystrophic mice (male 129/ReJ-dy and female 129 B6F1/J-dy) was examined to determine whether CNS abnormalities accompany the known muscular defects. Brain N-acetyl-L-aspartate, aspartate, and glutamate were significantly lower than in brain from control mice. These amino acids are only slightly reduced in brains of female dystrophic mice.
摘要
对肌营养不良小鼠（雄性129/ReJ-dy和雌性129 B6F1/J-dy）的脑组织进行检查，以确定中枢神经系统异常是否伴随已知的肌肉缺陷。脑内N-乙酰-L-天冬氨酸、天冬氨酸和谷氨酸的含量显著低于对照小鼠脑内的含量。在雌性营养不良小鼠的脑中，这些氨基酸仅略有减少。
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