Hayashi N, Green B A, Mora J, González-Carvajal M, Veraa R P
Neurol Res. 1983;5(4):49-58. doi: 10.1080/01616412.1983.11758588.
Measurement of local blood flow by hydrogen clearance is a useful technique and is compatible with simultaneous measurement of oxygen tension over long periods. However, existing methods present serious limitations of spatial resolution due to high diffusion rates and other factors. Improved methods permit local measurements in both gray and white matter of the rat spinal cord that correlate well with data from autoradiographic techniques, and indeed distinguish between individual gray matter laminae. Applications of similar methods should be useful in other systems where high spatial resolution is required.
通过氢清除法测量局部血流是一项有用的技术，并且能够与长时间同步测量氧张力兼容。然而，由于高扩散率和其他因素，现有方法在空间分辨率方面存在严重局限性。改进后的方法能够在大鼠脊髓的灰质和白质中进行局部测量，这些测量结果与放射自显影技术的数据高度相关，甚至能够区分各个灰质层。类似方法的应用在需要高空间分辨率的其他系统中应该会很有用。
