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大鼠脊髓中的局部血流、氧张力和氧消耗。第1部分:氧代谢与神经元功能。

Local blood flow, oxygen tension, and oxygen consumption in the rat spinal cord. Part 1: Oxygen metabolism and neuronal function.

作者信息

Hayashi N, Green B A, Gonzalez-Carvajal M, Mora J, Veraa R P

出版信息

J Neurosurg. 1983 Apr;58(4):516-25. doi: 10.3171/jns.1983.58.4.0516.

DOI:10.3171/jns.1983.58.4.0516
PMID:6402568
Abstract

A reliable and reproducible microelectrode technique provided consistent simultaneous measurements of local spinal cord blood flow (local SCBF), tissue oxygen tension (TO2), and tissue oxygen consumption (TO2C) in the rat. Local SCBF was measured by the hydrogen clearance technique, local TO2 was measured polarographically, and local TO2C was calculated from the declining slope of local TO2 following temporary arrest of local SCBF. Mean local TO2 values varied only slightly between gray and white matter, while local TO2C and SCBF maintained a 3 to 1 ratio between gray and white matter areas. Measurements were also made of these parameters in specific white matter tracts and laminae of Rexed. Local white matter SCBF was relatively homogeneous throughout the ventral, lateral, and dorsal funiculi. Gray matter blood flow was more variable with topography. The highest local SCBF was recorded in areas rich in internuncial neurons. The somatic motor regions had values slightly higher than recorded in sensory regions.

摘要

一种可靠且可重复的微电极技术能够对大鼠局部脊髓血流量(局部SCBF)、组织氧张力(TO2)和组织氧消耗(TO2C)进行一致的同步测量。局部SCBF通过氢清除技术测量,局部TO2通过极谱法测量,局部TO2C则根据局部SCBF暂时停止后局部TO2的下降斜率计算得出。灰质和白质之间的平均局部TO2值仅略有差异,而局部TO2C和SCBF在灰质和白质区域之间保持3比1的比例。还对Rexed特定白质束和板层中的这些参数进行了测量。整个腹侧、外侧和背侧索的局部白质SCBF相对均匀。灰质血流随地形变化更大。局部SCBF最高值记录在富含联络神经元的区域。躯体运动区域的值略高于感觉区域记录的值。

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Local blood flow, oxygen tension, and oxygen consumption in the rat spinal cord. Part 1: Oxygen metabolism and neuronal function.大鼠脊髓中的局部血流、氧张力和氧消耗。第1部分:氧代谢与神经元功能。
J Neurosurg. 1983 Apr;58(4):516-25. doi: 10.3171/jns.1983.58.4.0516.
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Evidence that nitric oxide- and opioid-containing interneurons innervate vessels in the dorsal horn of the spinal cord of rats.
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