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[感觉运动皮层神经元参与食物及定向探索行为的神经化学机制]

[Neurochemical mechanisms of the involvement of sensorimotor cortex neurons in food and orienting-exploratory behavior].

作者信息

Sudakov S K, Meshcheriakov A F, Sterio G

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1984 Sep;70(9):1311-5.

PMID:6149963
Abstract

Reactions of individual neurons to electrical stimulation of motivational areas of the lateral hypothalamus were studied in the somatosensory cortex of alert rabbits during micro. iontophoretic application of acetylcholine, norepinephrine or cycloheximide. The former two drugs altered equally the neuron reactions both on weak (inducing an orienting response) and strong stimulation (causing feeding behaviour). The latter drug also affected the neuron reactions. The feeding and orienting responses seem to be actualized through a specific peptide synthesis in the somatosensory cortex's neurons altering their sensitivity to neurotransmitters.

摘要

在清醒家兔的体感皮层进行微量离子电泳施加乙酰胆碱、去甲肾上腺素或环己酰亚胺时,研究了单个神经元对下丘脑外侧动机区电刺激的反应。前两种药物对弱刺激(诱发定向反应)和强刺激(引起进食行为)时的神经元反应改变程度相同。后一种药物也影响神经元反应。进食和定向反应似乎是通过体感皮层神经元中特定肽的合成来实现的,这种合成改变了它们对神经递质的敏感性。

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