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[在微量离子电泳给予胃泌素和缓激肽的背景下,感觉运动皮层对下丘脑外侧刺激的神经元反应:食物强化的作用]

[The neuronal reaction of the sensorimotor cortex to stimulation of the lateral hypothalamus with a background of the microiontophoretic administration of tetragastrin and bradykinin: the role of food reinforcement].

作者信息

Kravtsov A N, Sudakov S K

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1995 Jul-Aug;45(4):757-64.

PMID:8540260
Abstract

Reactions of neurons of sensorimotor cortex to stimulation of the "center of hunger" in the lateral hypothalamus were studied at the background of microiontophoretic application of gastrin, and bradikinin in satiated freely behaving rabbits under conditions of presence or absence of free access to food. It was shown that food reinforcement essentially changed reactions of neurons to electrical stimulation of the lateral hypothalamus at the background of application of neuropeptides under study. This probably led to specific reorganization in the neuronal system which underlay the mechanism of interaction between motivation and reinforcement influences on the neurons.

摘要

在自由活动且已饱食的家兔中,在有或没有自由获取食物的条件下,研究了感觉运动皮层神经元对下丘脑外侧“饥饿中枢”刺激的反应,同时在微离子电泳应用胃泌素和缓激肽的背景下进行研究。结果表明,在应用所研究的神经肽的背景下,食物强化显著改变了神经元对下丘脑外侧电刺激的反应。这可能导致神经元系统发生特定的重组,而该重组是动机与强化对神经元的影响之间相互作用机制的基础。

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