胶原蛋白对抗凝血酶III和肝素灭活凝血酶的影响。
Effect of collagen on thrombin inactivation by antithrombin-III and heparin.
作者信息
Blaskó G, Bédi J, Machovich R, Pálos L A
出版信息
Haematologia (Budap). 1977;11(1-2):163-8.
PMID:615087
Abstract
Thrombin inactivation by antithrombin-III and heparin has been found to decrease in the presence of collagen, whereas thrombin activity and the rate of thrombin inactivation by antithrombin-III alone are not affected. Albumin, at the same concentration as collagen, does not influence either thrombin activity or thrombin inactivation by antithrombin-III or by antithrombin-III plus heparin.
摘要
已发现，在胶原蛋白存在的情况下，抗凝血酶III和肝素对凝血酶的灭活作用会降低，而凝血酶活性以及仅由抗凝血酶III对凝血酶的灭活速率不受影响。与胶原蛋白浓度相同的白蛋白，既不影响凝血酶活性，也不影响抗凝血酶III或抗凝血酶III加肝素对凝血酶的灭活作用。
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