König H J, Brandt M
Neurochirurgia (Stuttg). 1980 Jan;23(1):7-13. doi: 10.1055/s-2008-1053481.
As result of a poll, the opinion of 50 Neurosurgical Departments in the Federal Republic of Germany relating to the importance of hypophysectomy in the therapy of metastatic carcinoma of the breast was obtained. Four of 32 replies prefer a regular hypophysectomy and 11 departments do the hypophysectomy only in exceptional cases. In 17 clinics this operation is not used. It should be emphasized, that a quarter of those neurosurgeons, who took part in our inquiry, had already given up hypophysectomy some years ago. About 50% of the surgeons talk about positive effects on metastatic carcinomas. The hormonal dependence of disseminated cancers is the only condition, which has to be presumed. Implantation of radioisotopes and trans-sphenoidal hypophysectomy are mentioned as the main operative techniques. The indications for hypophysectomy for metastatic carcinoma of the breast are discussed in the light of the recent literature. If one considers the possibilities of radiotherapy and chemotherapy, hypophysectomy can still be of considerable value as a palliative measure in hormone-dependent tumours with bone metastases, provided that the cases are carefully selected.
通过一项民意调查，了解了德意志联邦共和国50个神经外科科室对垂体切除术在乳腺癌转移癌治疗中的重要性的看法。32份回复中有4份倾向于常规垂体切除术，11个科室仅在特殊情况下进行垂体切除术。在17家诊所中，该手术未被采用。应该强调的是，参与我们调查的神经外科医生中有四分之一在几年前就已经放弃了垂体切除术。约50%的外科医生谈到对转移癌有积极作用。必须假定播散性癌症的激素依赖性是唯一条件。放射性同位素植入和经蝶窦垂体切除术被提及为主要手术技术。根据最近的文献讨论了乳腺癌转移癌垂体切除术的适应症。如果考虑到放疗和化疗的可能性，对于有骨转移的激素依赖性肿瘤，垂体切除术作为一种姑息性措施仍可能具有相当大的价值，前提是病例经过仔细挑选。
