Hardy J, Grisoli F, Leclercq T A, Somma M
Nouv Presse Med. 1975 Oct 11;4(33):2387-90.
160 patients suffering from advanced metastatic cancer of the breast had transsphenoidal open surgical hypophysectomy. Mortality (1,8 p.cent) and morbidity were extremely low in view of the general conditions of the patients. Immediate relief of pain due to bone metastasis was obtained in 92 p.cent of cases. Such results emphasized the important point of achieving total hypophysectomy.
160例晚期转移性乳腺癌患者接受了经蝶窦开放性手术垂体切除术。鉴于患者的总体状况，死亡率（1.8%）和发病率极低。92%的病例因骨转移导致的疼痛立即得到缓解。这些结果强调了实现全垂体切除术这一要点的重要性。
