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[临床应用的血清脂肪酶测定。批判性研究(作者译)]

[Serum lipase assay for clinical use. Critical study (author's transl)].

作者信息

Fruchart J C, Sezille G, Ghisbain H, Hassoun A, Choteau P, Arbon G, Quandalle P, Ribet M

出版信息

Nouv Presse Med. 1980 Feb 16;9(8):509-12.

PMID:6154284
Abstract

An accurate, quick, and reproducible method to assay serum lipase activity allowed a parallel study of lipase and amylase in 147 patients. Lipase appeared very specific of pancreatic distress. In acute pancreatitis its increase was constant, frank, quick and lasting. It brought a diagnostic argument superior to the dosages of amylase activities in serum and/or urine. But its value as an evolutive and pronostic test was as much limited. Its interest as a negative argument for differential diagnosis was not superior either. In chronic pancreatic diseases, it gave evidence of massive spread or complications.

摘要

一种准确、快速且可重复的血清脂肪酶活性检测方法,使得对147例患者的脂肪酶和淀粉酶进行了平行研究。脂肪酶似乎对胰腺病变具有高度特异性。在急性胰腺炎中,其升高是持续、明显、迅速且持久的。它提供了一种比血清和/或尿液中淀粉酶活性测定更具诊断价值的依据。但其作为病情演变和预后检测的价值同样有限。其作为鉴别诊断的阴性依据的价值也并不突出。在慢性胰腺疾病中,它显示出广泛扩散或并发症的迹象。

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