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系统性硬化症患者的振动觉

Vibratory perception in patients with generalized scleroderma.

作者信息

Dahlgaard T, Nielsen V K, Kristensen J K

出版信息

Acta Derm Venereol. 1980;60(2):119-22.

PMID:6155016
Abstract

The vibratory perception threshold (VPT) was measured on eight different test-spots in 13 patients suffering from generalized scleroderma of the acrosclerosis type without clinical evidence of peripheral neuropathy. VPT was significantly elevated in skin areas severely involved in the sclerodermic process, whereas normal on test-spots with less affected skin. The pattern of impaired vibratory perception differs from that usually seen in peripheral neuropathy and it is concluded that the pattern most probably reflects the viscous-elastic properties of the test-spots, indicating that cutaneous sclerosis exerts a damping effect on external vibrations. It is suggested that this phenomenon could be utilized as an objective gauge for the severity of the sclerosis.

摘要

对13例患有肢端硬化型全身性硬皮病且无周围神经病变临床证据的患者,在8个不同测试点测量了振动觉阈值(VPT)。在硬皮病病变严重的皮肤区域,VPT显著升高,而在皮肤受累较轻的测试点则正常。振动觉受损的模式不同于周围神经病变中常见的模式,得出的结论是,该模式很可能反映了测试点的粘弹性特性,表明皮肤硬化对外界振动有阻尼作用。有人提出,这种现象可用作评估硬化严重程度的客观指标。

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