Vassilopoulos D, Lumb E M, Emery A E
Eur Neurol. 1977;16(1-6):31-4. doi: 10.1159/000114877.
Human muscle cell growth was studied to investigate the nucleo-cytoplasmic ratio during development and ageing. The mean muscle fibre size, as well as the number and size of myonuclei were estimated in human muscle biopsies from normal individuals whose ages ranged from 1 to 71 years. Changes in muscle fibre size were accompanied by similar changes in nuclear number, the size of which remained the same. This resulted in a constant nucleo-cytoplasmic ratio during the age range studied. The role of the satellite cell in the maintenance of this ratio was discussed.
为了研究发育和衰老过程中的核质比，对人类肌肉细胞生长进行了研究。在年龄从1岁到71岁的正常个体的肌肉活检样本中，估计了平均肌纤维大小以及肌细胞核的数量和大小。肌纤维大小的变化伴随着核数量的类似变化，而核的大小保持不变。这导致在所研究的年龄范围内核质比保持恒定。文中讨论了卫星细胞在维持这一比例中的作用。
