与Q热心内膜炎相关的系膜毛细血管性肾小球肾炎。

Mesangio-capillary glomerulonephritis associated with Q-fever endocarditis.

作者信息

Uff J S, Evans D J

出版信息

Histopathology. 1977 Nov;1(6):463-72. doi: 10.1111/j.1365-2559.1977.tb01685.x.

DOI:10.1111/j.1365-2559.1977.tb01685.x

Abstract

A patient with nephrotic syndrome and Q-fever endocarditis (confirmed serologically and ultrastructurally) was found to have mesangio-capillary glomerulonephritis with parietal deposits of C3 and IgM and some IgM in the mesangium. Elution studies showed that IgM antibodies reactive against insoluble Coxiella antigens were present in the kidney. Review of the literature suggests that this type of immune complex nephritis may be associated with Q-fever. Possible reasons for the variability of the nephritis associated with infective endocarditis are discussed.

摘要

一名患有肾病综合征和Q热心内膜炎（经血清学和超微结构确诊）的患者被发现患有系膜毛细血管性肾小球肾炎，伴有C3和IgM的壁层沉积以及系膜中的一些IgM。洗脱研究表明，肾脏中存在针对不溶性柯克斯体抗原的IgM抗体。文献回顾提示，这种类型的免疫复合物性肾炎可能与Q热有关。文中讨论了与感染性心内膜炎相关的肾炎变异性的可能原因。