Wallow I H, Geldner P S
Invest Ophthalmol Vis Sci. 1980 Oct;19(10):1176-83.
The ultrastructure of old neovascular preretinal membranes was examined in both eyes of a patient with proliferative diabetic retinopathy treated in one eye with photocoagulation. Membranes in both eyes consisted of a matrix rich in mature collagen surrounding viable new vessels and "ghost vessels." Viable vessels of different calibers frequently showed endothelial fenestrae bridged by diaphragms. Occasionally tight junctions between endothelial cells appeared altered. Fenestrae and incompetent junctions may account for the characteristic "leakiness" of newly formed vessels.
对一名增殖性糖尿病视网膜病变患者的双眼进行了检查，该患者一只眼睛接受了光凝治疗，观察了其陈旧性视网膜前新生血管膜的超微结构。双眼的膜均由富含成熟胶原的基质组成，围绕着存活的新血管和“幽灵血管”。不同管径的存活血管常可见由隔膜桥接的内皮窗孔。偶尔可见内皮细胞间的紧密连接出现改变。窗孔和功能不全的连接可能是新形成血管具有特征性“渗漏”的原因。
